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- Take Prometrium by mouth with or without food.
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Ask your health care provider any questions you may have about how to use Prometrium.
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Do NOT use Prometrium if:
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Contact your doctor or health care provider right away if any of these apply to you.
Some medical conditions may interact with Prometrium. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
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Seek medical attention right away if any of these severe side effects occur:
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