If there was a clinically important difference between the groups but the sample size was small generic 10mg reglan with mastercard, a marginal p value would suggest that a type ii error had occurred and that a larger, more definitive study was warranted.
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Reglan is used for 4 to 12 weeks to treat heartburn caused by gastroesophageal reflux in people who have used other medications without relief.
Renal impairment affects the clearance of metoclopramideIn a study with patients with varying degrees of renal impairmenta reduction in creatinine clearance was correlated with a reduction in plasma clearancerenal clearancenon-renal clearanceand increase in elimination half-lifeThe kinetics of metoclopramide in the presence of renal impairment remained linear howeverThe reduction in clearance as a result of renal impairment suggests that adjustment downward of maintenance dosage should be done to avoid drug accumulation.
Metoclopramide is contraindicated in patients with known sensitivity or intolerance to the drugMetoclopramide should not be used in epileptics or patients receiving other drugs which are likely to cause extrapyramidal reactionssince the frequency and severity of seizures or extrapyramidal reactions may be increased.
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