You should restrict your alcohol consumption when using vytorin because alcohol increases triglyceride levels in your body and this combined with the use of vytorin may cause serious liver damage.
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There have been rare postmarketing reports of cognitive impairmente.gmemory lossforgetfulnessamnesiamemory impairmentconfusionassociated with statin useThese cognitive issues have been reported for all statinsThe reports are generally nonseriousand reversible upon statin discontinuationwith variable times to symptom onset1 day to yearsand symptom resolutionmedian of 3 weeks
VYTORIN therapy should be discontinued if markedly elevated CPK levels occur or myopathy is diagnosed or suspectedVYTORIN therapy should also be temporarily withheld in any patient experiencing an acute or serious condition predisposing to the development of renal failure secondary to rhabdomyolysise.gsepsishypotensionmajor surgerytraumasevere metabolicendocrineor electrolyte disordersor uncontrolled epilepsy.
The safety and effectiveness of VYTORIN administered with fibrates have not been establishedBecause it is known that the risk of myopathy during treatment with HMG-CoA reductase inhibitors is increased with concurrent administration of fenofibratesVYTORIN should be administered with caution when used concomitantly with a fenofibratesee WARNINGS AND PRECAUTIONS
Do not increase your dose or take this medication more often than prescribedYour condition will not improve any fasterand the risk of serious side effects may be increased.
In additionan apparent hypersensitivity syndrome has been reported rarely that has included one or more of the following featuresanaphylaxisangioedemalupus erythematous-like syndromepolymyalgia rheumaticadermatomyositisvasculitispurpurathrombocytopenialeukopeniahemolytic anemiapositive ANAESR increaseeosinophiliaarthritisarthralgiaurticariaastheniaphotosensitivityfeverchillsflushingmalaisedyspneatoxic epidermal necrolysiserythema multiformeincluding Stevens-Johnson syndrome.
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in this trial, patients with acute coronary syndrome acs were randomized to receive either vytorin or simvastatin alone.