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Pharmacokinetic parameters were calculated by a noncompartmental methodPlasmatic concentrations versus time were averaged by administered dose and for each sampling timeFor each parameter the following was calculatedAveragegeometric averagestandard deviationvariation quotientminimummaximum and number of determinations.
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A study monitor from the sponsor supervised that the study was conducted according to the study protocolthe Good Clinical Practice and the Mexican national regulation.
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