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TABLE 2Adverse Events Associated with Discontinuation of Treatment in Short-TermPlacebo-ControlledDepression Trials.
The stated frequencies of adverse events represent the proportion of individuals who experiencedat least oncea treatment-emergent adverse event of the type listedAn event was considered treatmentemergent if it occurred for the first time or worsened while receiving therapy following baseline evaluation.
At least 14 days should elapse between discontinuation of an MAOI intended to treat psychiatric disorders and initiation of therapy with CelexaConverselyat least 14 days should be allowed after stopping Celexa before starting an MAOI intended to treat psychiatric disorderssee CONTRAINDICATIONS
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if lapatinib will be coadministered with a cyp3a4 substrate, such as citalopram, exercise caution and consider dose reduction of citalopram.