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Take Neurontin exactly as prescribed by your doctorFollow all directions on your prescription labelDo not take this medicine in larger or smaller amounts or for longer than recommended.

Gabapentin does not exhibit affinity for benzodiazepineopiatemudelta or kappaor cannabinoid 1 receptor sitesA small number of postmarketing cases report gabapentin misuse and abuseThese individuals were taking higher than recommended doses of gabapentin for unapproved usesMost of the individuals described in these reports had a history of poly-substance abuse or used gabapentin to relieve symptoms of withdrawal from other substancesWhen prescribing gabapentin carefully evaluate patients for a history of drug abuse and observe them for signs and symptoms of gabapentin misuse or abusee.gdevelopment of toleranceself-dose escalationand drug-seeking behavior

This Medication Guide summarizes the most important information about NEURONTINIf you would like more informationtalk with your healthcare providerYou can ask your healthcare provider or pharmacist for information about NEURONTIN that was written for healthcare professionals.

Antiepileptic drugsAEDsincluding NEURONTINincrease the risk of suicidal thoughts or behavior in patients taking these drugs for any indicationPatients treated with any AED for any indication should be monitored for the emergence or worsening of depressionsuicidal thoughts or behaviorand/or any unusual changes in mood or behavior.

Patients should be carefully observed for signs of central nervous systemCNSdepressionsuch as somnolence and sedationwhen NEURONTIN is used with other drugs with sedative properties because of potential synergyIn additionpatients who require concomitant treatment with morphine may experience increases in gabapentin concentrations and may require dose adjustmentsee DRUG INTERACTIONS

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